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Iranian forces say they have struck a US naval base in Manama, as Iran launched operations throughout the Middle East in response for a significant and continuing attack against it by the United States and Israeli forces.

Large columns of dark smoke were observed billowing from an area near the main base of the US Navy's Fifth Fleet in Manama, Bahrain. The full scale of any damage is not yet known and the US has remained silent.

Missile Defenses Activated

In other parts of the Middle East, the UAE, Qatar and Kuwait - which all house US military bases - stated they have intercepted missiles in their territorial skies.

In Doha, Qatar's defence ministry announced it had successfully engaged several missiles seemingly aimed at the al-Udeid air base, the largest American base in the Middle East.

IRGC Statement

The Iranian Revolutionary Guard said in a statement it was attacking American facilities and interests as part of operation "Truthful Promise 4", in response for the offensive on the Islamic Republic initiated by the United States and its ally Israel on Saturday.

That US-Israeli operation - launched at approximately 09:15 Iran time - has so far struck locations associated with the Tehran's leadership, with President Trump urging the Iranian people to revolt against the government.

Additional Developments

In Israel, sirens were heard nationwide after the Israel Defense Forces stated it had detected an incoming Iranian missile barrage.

The Ministry of Defence of the United Arab Emirates stated that the nation has been targeted by a "a blatant attack involving Iranian ballistic missiles".

"Emirati air defenses responded to the missiles with high efficiency and successfully intercepted a series of missiles," the statement continued.

It said wreckage landed in a residential area in the capital, causing some structural damage and fatalities.

The United States Air Force is stationed at Al Dhafra Air Base, to the south of the Emirati capital, along with the Emirati Air Force.